Ige antibodies generation and function juan j lafaille maria a curotto de lafaille eds this volume examines all facets of the complex biology of immunoglobulin e ige antibodies which play an essential role in the pathophysiology of allergic diseases and immunity to parasites series current topics in microbiology and immunology . Ige antibodies generation and function current topics in microbiology and immunology 9783319137247 medicine health science books amazoncom skip to main content try prime books go search en hello sign in account lists sign in account lists orders try prime cart . Part of the current topics in microbiology and immunology book series ct microbiology volume 388 abstract the immune response against helminths and allergens is generally characterized by high levels of ige and increased numbers of th2 cells eosinophils and mast cells yet the clinical outcome with respect to immediate hypersensitivity and . Hannah j gould rebecca l beavil in encyclopedia of immunology second edition 1998 ige immunoglobulin e is the least abundant but in many respects the most potent of the various antibody classes found in mammalsin normal individuals the concentration of ige in serum 100 ng ml 1 is 10000 times less than that of igg 15 mg ml 1 but it is elevated in allergic individuals in . Ige antibodies to iga have been reported to cause severe transfusion reactions in iga deficient patients 7 there are a few reports of true anaphylaxis in patients with selective iga deficiency and with common variable immunodeficiency who developed ige antibodies to iga after treatment with immunoglobulin 7 the serum levels of ige antibody against iga were found to correlate with anaphylaxis
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